Sihauli Chemicals Private Limited

Calamine lotion is an over-the-counter (OTC) medicine you can use to treat mild itchiness (pruritus). The topical pink lotion can help relieve itchiness, pain and discomfort caused by conditions such as bug bites, chickenpox and poison ivy.Calamine is used to relieve the itching, pain, and discomfort of minor skin irritations, such as those caused by poison ivy, poison oak, and poison sumac. This medicine also dries oozing and weeping caused by poison ivy, poison oak, and poison sumac.Calamine has a mild astringent action of the skin and is used as a dusting powder, cream, lotion or ointment in a variety of skin conditions. Zinc oxide has a mildly antiseptic action and is a mild astringent, it has soothing and protective properties.

• Quality Control:Strict quality control measures are essential in pharmaceutical production to ensure the purity, safety, and efficacy of the final product. 
• Sterilization:The formulation and manufacturing process must be designed to ensure sterility, preventing microbial contamination. 
• Packaging:Appropriate packaging is needed to protect the product from contamination and degradation. 
• Labeling:Clear and accurate labeling is crucial to inform consumers about the product's intended use, ingredients, and any necessary precautions
  • Calamine lotion13 Jan 2022 — Calamine lotion is a shake lotion composed of calamine (zinc oxide/carbonate and ferric oxide), zinc oxide, bentonite,Journal of Skin and Sexually Transmitted Diseases
  • Calamine Lotion: Uses, Benefits & Side Effects - Cleveland Clinic24 Jun 2022 — Calamine lotion contains the active ingredients zinc oxide and 0.5% iron oxide. The iron oxide gives calamine lotion it...Cleveland Clinic
  • Calamine - WikipediaIt is considered to be safe in pregnancy. Calamine is a combination of zinc oxide and 0.5% ferric oxide (Fe2O3). The lotion is pro...Wikipedia
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  This is for informational purposes only. For medical advice or diagnosis, consult a professional. Generative AI is experimental.
• Sourcing and Quality Control: Pharmaceutical companies source calamine (which itself is a mixture of zinc oxide with a small amount of ferric oxide) and zinc oxide as raw materials. Rigorous quality control testing is performed on these raw materials to ensure they meet pharmacopoeial standards for purity, identity, and assay before being used in manufacturing.
• Wet Grinding and Mixing: The manufacturing of calamine lotion typically involves wet grinding of calamine and zinc oxide to achieve a fine particle size, followed by mixing with other ingredients like glycerol, bentonite magma, and purified water to create the final suspension. Pharmaceutical manufacturing processes adhere to strict Good Manufacturing Practices (GMP) to ensure product quality and consistency.  
• Pharmaceutical industries must adhere to stringent regulatory guidelines set by health authorities (e.g., FDA in the United States, EMA in Europe, CDSCO in India) for the manufacturing and marketing of OTC drugs like calamine lotion. This includes:Formulation Development: Pharmaceutical scientists utilize their knowledge of the properties of calamine and zinc oxide when developing new topical products. They consider factors like particle size, dispersibility, and interaction with other ingredients.

Ethyl decanoate, also known as ethyl caprate, is a fatty acid ester formed from capric acid and ethanol. This ester is a frequent product of fermentation during winemaking, especially at temperatures above 15 °C